South Rampart Pharma Secures $8M Series A to Pioneer a Safer, Non-Addictive Pain Relief Revolution

South Rampart Pharma, Inc. is thrilled to announce that it has successfully raised $8,000,000 in its latest funding round, marking a significant milestone in its mission to transform pain management. As a clinical-stage biotech company, South Rampart Pharma is tackling one of the most critical unmet needs in medicine: safe and effective pain relief. The recent infusion of capital will play a pivotal role in advancing the development of its lead clinical candidate, SRP-001, a novel, first-in-class analgesic. Uniquely designed to activate pain signaling pathways in the midbrain’s periaqueductal grey (PAG) region, SRP-001 has demonstrated promising efficacy in several pain models—including inflammatory, visceral, and somatic pain—by modulating endocannabinoid, mechanical nociception, and fatty acid amide hydrolase pathways. Unlike traditional opioids, which carry high risks of abuse and addiction, SRP-001 offers a safer alternative, as it does not pose such risks, nor does it have the hepatotoxicity associated with acetaminophen, which is often linked to dangerous metabolites like NAPQI. The funding will be strategically allocated to further clinical trials, enhance research and development efforts, and expedite regulatory pathways to bring this innovative therapy to patients in need. Initial Phase 1 trial data (NCT05484414) have already underscored SRP-001’s favorable safety and tolerability profile, along with encouraging pharmacokinetic properties. With this capital raise, South Rampart Pharma is poised to deepen its investigation into SRP-001’s full potential, ultimately providing a groundbreaking and safer alternative to conventional pain medications, including NSAIDs and opioids. This investment is a testament to the confidence in South Rampart Pharma’s vision to revolutionize pain management and improve countless lives.