Inozyme Pharma Secures $270M to Accelerate Revolutionary INZ-701 Development for Rare Diseases

Inozyme Pharma is thrilled to announce a remarkable funding milestone, having successfully raised $270 million to accelerate its mission of developing transformative treatments for rare diseases that impact bone health and blood vessel function. As a pioneering, clinical-stage biopharmaceutical company, Inozyme Pharma has built its reputation on a commitment to innovation and scientific excellence, particularly in the realm of conditions with limited therapeutic options. The recently secured capital will serve as a catalytic force to advance the company's lead candidate, INZ-701—an innovative ENPP1 Fc fusion protein enzyme replacement therapy (ERT) designed to increase the levels of pyrophosphate (PPi) and adenosine. By leveraging the unique potential of the PPi-adenosine pathway, INZ-701 targets the underlying causes of pathological mineralization and intimal proliferation, which are central contributors to the morbidity and mortality observed in diseases such as ENPP1 Deficiency, ABCC6 Deficiency, and calciphylaxis. This significant investment not only validates Inozyme Pharma’s strategic vision but also underscores the confidence that investors have in the company’s science and clinical approach. The funds will be instrumental in furthering clinical development, expanding research initiatives, and supporting critical operational milestones so that the promise of INZ-701 can be fully realized. As Inozyme Pharma moves forward, the company remains steadfast in its pursuit of innovative, life-changing therapeutics, with a focus on addressing rare and complex conditions that have long challenged the medical community. This funding round marks an important chapter, paving the way for accelerated clinical trials and, ultimately, improved patient outcomes.